Spiders aren’t dangerous to humans, but who enjoy watching this 8-leg crawlies running around?
Here are the best insecticides for spiders you can buy in 2025:
- Best Overall: Ortho Home Defense Insect Killer for Indoor & Perimeter2 Ready-To-Use Trigger Sprayer
- Best for Hard-To-Reach Places: Hot Shot Indoor Fogger With Odor Neutralizer, 4/2-Ounce
- Best for Spider Mites: Hot Shot 100046114 No-Pest Strip
- Best For Wolf Spiders: Demon Max 070294125000
- Fast- Working: BASF 792075 – Insecticide
- Best for Hobo Spiders: TERRO T2302 Spider Killer Aerosol Spray
6 Best Insecticides For Spiders | ||
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Best Overall | Ortho Home Defense Insect Killer for Indoor & Perimeter2 Ready-To-Use Trigger Sprayer | |
Best for Hard-To-Reach Places | Hot Shot Indoor Fogger With Odor Neutralizer, 4/2-Ounce | |
Best for Spider Mites | Hot Shot 100046114 No-Pest Strip | |
Best For Wolf Spiders | Demon Max 070294125000 | |
Fast- Working | BASF 792075 – Insecticide | |
Best for Hobo Spiders | TERRO T2302 Spider Killer Aerosol Spray |
Best Overall: Ortho Home Defense Insect Killer for Indoor & Perimeter2 Ready-To-Use Trigger Sprayer

Guarantees up to 12-month protection
Kill the most common household bugs
Odor-free
Non-staining
Ready to use
Suitable for both indoor and outdoor
- You can’t adjust the wand to make a powerful spray.
Ortho Home Defense Insect Killer can handle most types of roaches, ants, spiders, and 130 + other insects. If you are looking for an effective means to keep your house insect-free, this is a good option to try.
It can create a protective boundary within treating areas. Spiders can’t come near your kitchens, bathrooms or any doors or windows. Ortho keeps insects away from 3 to 12 months outside. It can treat up to 5300 sq.ft.
To use, you only need to connect to the garden hose and start spraying. This product is odor-free and non-staining.
Ortho Home Defense Insect Killer for Indoor & Perimeter2 Ready-To-Use Trigger Sprayer Specifications | |
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Usage Area | Outdoor and indoor |
Highlight Features | Connects to garden hose |
Ortho Home Defense Insect Killer creates a deadly barrier so that bugs and insects never bother you again.
Best for Hard-To-Reach Places: Hot Shot Indoor Fogger With Odor Neutralizer, 4/2-Ounce

Kills on contact
Doesn’t smell bad
No messy residue
Works with many types of insects
Reaches unreachable places
Treats up to 2000 cu.ft.
- Short effective period
Hot Shot Indoor Fogger is an effective spray against insects. Thanks to the flexible design, it can reach seemingly unreachable corners in your house. This product can be used in apartments, basements, boat cabins, campers, sheds, trailers, crawl spaces. It is super versatile.
Hot Shot Indoor Fogger might not work with fire ants, but it can handle most common insects, including houseflies, ticks, silverfish, moths, spiders and water bugs. This product is odorless. It doesn’t leave a mess after spraying. The treatment can reach up to 2000 cu.ft.
Despite the amazing results, Hot Shot offers a relatively short effective period. Within 2 months, you might need to spray again.
Hot Shot Indoor Fogger With Odor Neutralizer, 4/2-Ounce Specifications | |
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Weight | 1.07 pounds |
Usage Area | Indoor, outdoor |
Highlight Features | Treats 2,000 cubic feet of unobstructed space, suitable with different places |
Hot Shot Indoor Fogger With Odor Neutralizer, 4/2-Ounce is a versatile option to prevent insects in every corner in your house.
Best for Spider Mites: Hot Shot 100046114 No-Pest Strip

Odorless
Easy to use
Deep-penetrating vapor
Cost-effective
- Not made for a quick kill
Just like us, many insects love plants. Spider mites are one of them. They live mostly in North American, feeding booth indoor and outdoor plants. Spider mites nest under leaves. They live in a huge colony and can be very destructive to your garden.
Hot Shot 100046114 No-Pest Strip can help you with spider mites. It offers odorless vapor that distributes thoroughly in the treatment area. The product can kill both visible and invisible insects. It treats up to 4 months.
There are a few drawbacks. Hot Shot features chemicals that aren’t safe for human beings. You need to wear a mask and do not stay close to the treatment area. Plus, you can’t see quick knockdown like other insecticides.
Hot Shot 100046114 No-Pest Strip Specifications | |
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Weight | 2.4 ounces |
Usage Area | Indoor and outdoor |
Highlight Features | Treats up to 4 months |
Hot Shot 100046114 No-Pest Strip guarantees a spider mites-free house, protecting your indoor and outdoor house from this hungry insect.
Best For Wolf Spiders: Demon Max 070294125000

- Suitable for wolf spiders – the active ingredient Cypermethrin
- Easy to measure – the attached measuring cup
- It has a bad smell
Demon Max is a reliable stop-shop for economical and effective insecticides for spiders because it can be used in multiple different areas and can kill a wide range of spiders. If your home has an infestation of wolf spiders, the Demon Max 070294125000 is a solid choice.
Not only wolf spiders, this product can kill 30+ types of insect pests thanks to the active ingredient Cypermethrin.
According to the manufacturer, this product can offer up to 100% control after ten years in the soil.
As a wonderful plus, the attached measuring cup makes the measurement easy and mess-free.
Demon Max 070294125000 Specifications | |
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Weight | 16 Ounces |
Highlight Features | the active ingredient Cypermethrin the attached measuring cup |
If you have issues with wolf spiders, then the Demon Max 070294125000 is your best solution.
Fast- Working: BASF 792075 – Insecticide

- Fast-working & long-lasting - SmartCap microencapsulation technology
- Safe for indoor use – odorless and fast-drying
- Great insect control capability - 6% Cyfluthrin
- Take so much concentrate to treat an area
- Expensive
This insecticide contains 6% Cyfluthrin, an active ingredient known for its wonderful insect control capability.
Aside from spiders, this substance can kill flies, mosquitoes, fleas, weevils, termites, cockroaches, etc. It's commonly used in agriculture and residential settings.
Because this insecticide is odorless and fast-drying, it can be used indoors, too.
Making the BASF 792075 stand out from the competition is the use of SmartCap microencapsulation technology, which is fast-working and creates a longer-lasting residual activity. Per treatment, this product will last up to 90 days.
BASF 792075 – Insecticide Specifications | |
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Weight | 16 oz. |
Highlight Features | SmartCap microencapsulation technology odorless and fast-drying 6% Cyfluthrin |
Looking for a fast-working insecticide for spiders? Try the BASF 792075
Best for Hobo Spiders: TERRO T2302 Spider Killer Aerosol Spray

Rapid knockdown
No odor
Handles most species of spider
Long-lasting control
Versatile uses
Convenient
- Not pet-friendly
Boho spiders are among the most aggressive house spiders, especially during their nesting time. They like moist areas, dark hiding places, so they live in garages or basements.
Late summer and early fall are two periods when male hobo spiders wander to find mates and end up nesting crevices, cracks or dark places in your house.
If you don’t like hobo spiders running around your house, Terro Spider Skiller can help. This spray offers long-lasting residual control and instant kill. It can handle other insects such as ants, cockroaches, ticks, silverfish, and bedbugs.
You can spray Terror in any cracks and crevices or under cabinets, sinks, and fridges. You can also use it outside such as window frames, pipes, and walls. It is better to spray directly on spiders. The spraying bottle is easy to use and quite convenient.
If you have pets or children, make sure that you keep them away when spraying.
TERRO T2302 Spider Killer Aerosol Spray Specifications | |
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Weight | 4.8 ounces |
Usage Area | Indoor and outdoor |
Highlight Features | Rapid knockdown, Broad Treatment |
TERRO T2302 Spider Killer Aerosol Spray is the most convenient option to handle hobo spiders and other infestations around your house.
How To Choose The Best Insecticide For Spiders?
Safety
Insecticides are chemicals that are harmful to insects. However, these chemicals also threaten the safety of your children and pets.
Read carefully about the chemicals you are going to use. Plus, keep children and pets away from where you are treating.
Application
There are many ways to apply insecticides. You need to decide which one is the most effective. By addressing what problem, you are facing, you can select a suitable application.
Liquid, gas-based or solid insecticides work differently. Some kills instantly, some you need to wait.
Indoor vs Outdoor
Some insecticides only work indoor. Others can only handle spiders outdoor. Check the label carefully before buying it.
You also need to consider whether to kill insects outside, especially when you have a garden. Spiders help you get rid of unwanted bugs.
Types of Spiders
Though most insecticides claim they can handle most spiders, some types of spiders need more attention than others.
Some insecticides can handle web-building spiders but are completely useless to kill ground-dwelling species.
Make sure you buy the right insecticide for certain spiders.
Which Brands Make The Best Insecticide For Spiders?
Ortho
Ortho is a big name in the industry. The company provides affordable solutions for gardeners and homeowners to get rid of their insect problem once and for all.
Bayer
Bayer is a trusted place to go when you want an advanced method to completely remove insects from your house and garden. Bayer provides products that work both in low and high concentrations.
TERRO
TERRO is hands-down one of the best bug-killer companies. The company maintains its gold standard from the early day, delivering effective and versatile pest control solutions.
Tempo
Tempo offers a broad-spectrum method to handle insects and pests indoor and outdoor. The company is quite famous for its liquid powdered insecticides.
Hotshot
Hot Shot insecticides are powerful assistant in your war against pests. They give you a guarantee when it comes to killing insects.
FAQs
What chemical do exterminators use for spiders?
Most insecticide for spiders can handle most common household kinds; however, special types of spiders sometimes require different treatments. Exterminators often use ingredients such as cyfluthrin, deltamethrin or lambda-cyhalothrin to kill spiders and create a barrier to prevent spiders from coming into your house.
These chemicals are quite effective; however, you need to reapply them periodically.
What is a good spray for spiders?
A good spray needs to contain enough chemicals to kill spiders. Spays that contain low toxicity are highly recommended. Plus, a good spray should work even at low concentrations.
How do you get rid of spiders instantly?
If you aren’t friendly to those 8 legs, there are a few tips to get rid of them instantly.
When you first see spiders, try to catch them by using a jar or a glass. This is, of course, a friendly method since it spares the spider’s life. Make sure that the jar or glass is transparent, not too heavy or lightweight. It shouldn’t be too big.
Once you catch the spider in the jar, quickly slide the paper under it and lift the jar up. Bring the spider outside and maintain a good distance from your living area.
Other methods to chase spiders away without killing it including:
Relocate your trash bin: Spiders love flies and flies live in your trash bin.
Place horse chestnuts in your house where you see spiders.
Reduce the use of outdoor lights: light attracts insects, which attracts spiders to hunt.
Have eucalyptus as a house plant
Use cinnamon sticks or essential oils
Does spraying for spiders work?
It depends on how you use spray. If you spray directly on spiders, they can’t escape the chemicals. However, if you only spray on the ground, it is generally not so effective. Since spiders have long legs, they can keep their bellies off the ground.
Spraying on the ground can only keep spiders away for a short while.
What smells do spiders hate?
Spiders hate the smell of citrus fruits. Things like eucalyptus, lemon, tea tree, peppermint or cinnamon oils can chase spiders miles away. Spiders also don’t like the smell of vinegar.
Conclusion
It is quite difficult to get rid of spiders. That’s why you need the best insecticide for spiders to handle the job. These 6 amazing products I have reviewed above are absolutely effective and affordable to handle different types of spiders and the scale of infestation.